Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.96 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.96 |
| ▸ | FNTA | P49354 | 4/20 | 0.60 |
| ▸ | FNTB | P49356 | 4/20 | 0.60 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28486071 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL11404533 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL11410939 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL806825 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL806928 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL1301763 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL806725 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL1301765 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL133908 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL806690 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199587-A | Method of treating hypertension with polyprenyl alcohol ester | EISAI CO., LTD. (JP) | 1980-04-22 | — | — | US | claimed |
| JP-54076513-A | — | — | None | — | — | JP | disclosed |
| US-4175139-A | Hypertension treating agent containing polyprenyl alcohol | EISAI CO. LTD. (JP) | 1979-11-20 | — | — | US | disclosed |
| JP-S5476513-A | POLYPRENYL ALCOHOL ESTER AND HYPOTENSIVES CONTAINING IT | EISAI CO LTD | 1979-06-19 | — | — | JP | disclosed |