Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.96 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.96 |
| ▸ | FNTA | P49354 | 4/20 | 0.60 |
| ▸ | FNTB | P49356 | 4/20 | 0.60 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28486071 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL11404533 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL11410939 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL806825 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL806928 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL1301763 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL806725 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL1301765 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL11404530 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B | |
| SCHEMBL133908 | 1.00 | ALDH1A1 (0.96) | ALDH1A1ALOX15FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2014-08-28 | — | — | US | disclosed |
| WO-2012037069-A2 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243404-A1 | UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY | WEE1, WEE2, NOTUM | ALDH1A1 1556/4885ALOX15 161/4885FNTA 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.