Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435158 | 0.93 | HTR3E (0.33) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11414012 | 0.90 | HTR3E (0.35) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11422730 | 0.89 | FSCN1 (0.32) | NPC1RAB9AHTR3EHTR3BHTR3A | |
| SCHEMBL11277987 | 0.86 | KDM4E (0.34) | MEN1NPC1RAB9AKMT2AHTR3E | |
| SCHEMBL11408773 | 0.86 | PRSS1 (0.33) | LMNAKDM4E | |
| SCHEMBL11404860 | 0.86 | HTT (0.35) | MEN1HTTKMT2AKDM4E | |
| SCHEMBL11412581 | 0.85 | TSHR (0.30) | — | |
| Hydrochloric Acid SCHEMBL11269830 | 0.84 | KDM4E (0.33) | NPC1RAB9AHTR3EHTR3BHTR3A | |
| SCHEMBL11420391 | 0.83 | TRPV1 (0.35) | LMNAHTTRAB9ASMN1; SMN2KDM4E | |
| SCHEMBL11413270 | 0.83 | SMN1; SMN2 (0.34) | BDKRB1MEN1NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216229-A | 1-AMIDINO-3-PHENYLUREAS | WILLIAM H. RORER, INC. (US) | 1980-08-05 | — | — | US | disclosed |