Methyl Alcohol

Methyl Alcohol

SCHEMBL11405342

CO.COC(=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.37
DGAT1 O75907 1/20 0.34
LMNA P02545 3/20 0.33
F2 P00734 2/20 0.33
PRSS1 P07477 2/20 0.33
PRSS2 P07478 2/20 0.33
PRSS3 P35030 2/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
GAA P10253 1/20 0.32
KCNN4 O15554 1/20 0.31
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
NPC1 O15118 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2492481 0.97 ALDH1A1 (0.39) ALDH1A1THRBDGAT1LMNAF2
Ethane SCHEMBL8848638 0.95 ALDH1A1 (0.38) ALDH1A1THRBDGAT1LMNAF2
SCHEMBL2690305 0.90 THRB (0.48) ALDH1A1THRBDGAT1LMNAF2
SCHEMBL198030 0.88 THRB (0.52) ALDH1A1THRBDGAT1F2PRSS1
SCHEMBL196434 0.88 THRB (0.52) ALDH1A1THRBDGAT1F2PRSS1
SCHEMBL516962 0.88 THRB (0.52) ALDH1A1THRBDGAT1F2PRSS1
SCHEMBL2691635 0.88 THRB (0.52) ALDH1A1THRBDGAT1F2PRSS1
SCHEMBL497426 0.88 THRB (0.52) ALDH1A1THRBDGAT1F2PRSS1
SCHEMBL517150 0.88 THRB (0.52) ALDH1A1THRBDGAT1F2PRSS1
SCHEMBL674231 0.88 THRB (0.52) ALDH1A1THRBDGAT1F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4229263-A AZEOTROPES PHILLIPS PETROLEUM COMPANY (US) 1980-10-21 US claimed
US-4189615-A RELFUXING PHILLIPS PETROLEUM COMPANY (US) 1980-02-19 US claimed
US-4236975-A AZEOTROPES PHILLIPS PETROLEUM COMPANY (US) 1980-12-02 US disclosed
US-4236975-A AZEOTROPES PHILLIPS PETROLEUM COMPANY (US) 1980-12-02 US disclosed
US-4229263-A AZEOTROPES PHILLIPS PETROLEUM COMPANY (US) 1980-10-21 US disclosed
US-4229263-A AZEOTROPES PHILLIPS PETROLEUM COMPANY (US) 1980-10-21 US disclosed
US-4224112-A Recovery of 1,1-dihydroheptafluorobutanol from water by distillation PHILLIPS PETROLEUM COMPANY (US) 1980-09-23 US disclosed
US-4224112-A Recovery of 1,1-dihydroheptafluorobutanol from water by distillation PHILLIPS PETROLEUM COMPANY (US) 1980-09-23 US disclosed
US-4189615-A RELFUXING PHILLIPS PETROLEUM COMPANY (US) 1980-02-19 US disclosed
US-4189615-A RELFUXING PHILLIPS PETROLEUM COMPANY (US) 1980-02-19 US disclosed
US-4156791-A Preparation of alcohols by treating esters with alkali metal borohydride PHILLIPS PETROLEUM COMPANY (US) 1979-05-29 US disclosed
US-4156791-A Preparation of alcohols by treating esters with alkali metal borohydride PHILLIPS PETROLEUM COMPANY (US) 1979-05-29 US disclosed