Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29896184 | 1.00 | HSD17B10 (0.52) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL11007856 | 0.79 | ALDH1A1 (0.53) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL29291588 | 0.79 | ALDH1A1 (0.50) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL11045353 | 0.78 | ALDH1A1 (0.50) | HSD17B10ALDH1A1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL6757211 | 0.75 | CXCR1 (0.43) | HSD17B10ALDH1A1CYP3A4TSHRHPGD | |
| SCHEMBL11408277 | 0.74 | NOX1 (0.58) | ALDH1A1TDP1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL11411559 | 0.74 | KMT2A (0.51) | ALDH1A1TDP1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL1851955 | 0.74 | CXCR2 (0.57) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL9109201 | 0.73 | MEN1 (0.55) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL30531906 | 0.73 | MEN1 (0.55) | HSD17B10ALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |