Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287941 | 0.82 | RAPGEF4 (0.55) | GAAPOLBMAPTALDH1A1 | |
| SCHEMBL22838153 | 0.79 | NOX1 (0.55) | NOX1GAAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL30780064 | 0.79 | NOX1 (0.55) | NOX1GAAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL28748358 | 0.79 | NOX1 (0.55) | NOX1GAAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL9233011 | 0.79 | NOX1 (0.55) | NOX1GAAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL1999098 | 0.77 | GAA (0.55) | NOX1GAAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL6118251 | 0.77 | MAPK1 (0.63) | NOX1GAAPOLBMAPK1SMN1; SMN2 | |
| SCHEMBL11406554 | 0.76 | RAPGEF4 (0.56) | GAASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL30525199 | 0.76 | RAPGEF4 (0.56) | GAASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL11045353 | 0.76 | ALDH1A1 (0.50) | GAASMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |