Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | PTGIR | P43119 | 3/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040496 | 0.92 | PDE4D (0.39) | ALDH1A1LMNAABCC4PGRPOLB | |
| SCHEMBL11039587 | 0.92 | PDE4D (0.39) | ALDH1A1LMNAABCC4PGRPOLB | |
| SCHEMBL11406810 | 0.92 | PDE4D (0.39) | ALDH1A1LMNAABCC4PGRPOLB | |
| SCHEMBL10620207 | 0.92 | PDE4D (0.39) | ALDH1A1LMNAABCC4PGRPOLB | |
| SCHEMBL11400142 | 0.92 | PDE4D (0.39) | ALDH1A1LMNAABCC4PGRPOLB | |
| SCHEMBL11039586 | 0.92 | PDE4D (0.39) | ALDH1A1LMNAABCC4PGRPOLB | |
| SCHEMBL10624053 | 0.81 | PDE4D (0.42) | ALDH1A1LMNAABCC4PGRPOLB | |
| SCHEMBL10624047 | 0.81 | PDE4D (0.42) | ALDH1A1LMNAABCC4PGRPOLB | |
| SCHEMBL10619884 | 0.80 | ALDH1A1 (0.35) | ALDH1A1LMNAABCC4PGRPOLB | |
| SCHEMBL11489535 | 0.76 | PTGIR (0.46) | ALDH1A1LMNAABCC4PGRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038613-A1 | Novel prostaglandins E1 and anti-thrombotic compositions containing them | TEIJIN LIMITED (JP) | 1981-10-28 | — | — | EP | disclosed |
| EP-0019475-A2 | Process for preparing adjacently disubstituted ketones, novel prostaglandins E1 and anti-thrombotic compositions containing them | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | disclosed |