Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 5/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039586 | 1.00 | PDE4D (0.39) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11040496 | 1.00 | PDE4D (0.39) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11039587 | 1.00 | PDE4D (0.39) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11406810 | 1.00 | PDE4D (0.39) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11400142 | 1.00 | PDE4D (0.39) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11406772 | 0.92 | ALDH1A1 (0.31) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL10624047 | 0.88 | PDE4D (0.42) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL10624053 | 0.88 | PDE4D (0.42) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL24033096 | 0.82 | LMNA (0.40) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL9546206 | 0.82 | PPARG (0.38) | PDE4DPTGER3PTGER4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766147-A | ANTITUMOR AGENTS | TEIJIN LIMITED (JP) | 1988-08-23 | — | — | US | disclosed |
| EP-0106576-B1 | NOVEL 5-MEMBERED CYCLIC COMPOUNDS, PROCESS FOR THE PRODUCTION THEREOF, AND PHARMACEUTICAL USE THEREOF | TEIJIN LIMITED (JP) | 1988-03-09 | — | — | EP | disclosed |
| EP-0106576-A2 | Novel 5-membered cyclic compounds, process for the production thereof, and pharmaceutical use thereof | TEIJIN LIMITED (JP) | 1984-04-25 | — | — | EP | disclosed |