Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CDC25A | P30304 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.67 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1140731 | 1.00 | VDR (0.67) | VDRMAPTMEN1KMT2ACDC25A | |
| SCHEMBL22141545 | 0.88 | MAPT (0.77) | VDRMAPTMEN1KMT2ACDC25A | |
| SCHEMBL23619148 | 0.88 | MAPT (0.77) | VDRMAPTMEN1KMT2ACDC25A | |
| SCHEMBL4993254 | 0.88 | MAPT (0.77) | VDRMAPTMEN1KMT2ACDC25A | |
| SCHEMBL1650555 | 0.88 | MAPT (0.77) | VDRMAPTMEN1KMT2ACDC25A | |
| SCHEMBL16645293 | 0.88 | MAPT (0.63) | VDRMAPTMEN1KMT2ACDC25A | |
| SCHEMBL19988240 | 0.86 | VDR (0.60) | VDRMAPTMEN1KMT2ACDC25A | |
| SCHEMBL21128778 | 0.85 | MAPT (0.80) | VDRMAPTMEN1KMT2ACDC25A | |
| SCHEMBL21264751 | 0.85 | MAPT (0.80) | VDRMAPTMEN1KMT2ACDC25A | |
| SCHEMBL12372105 | 0.85 | MAPT (0.80) | VDRMAPTMEN1KMT2ACDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180320139-A1 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | GAMIDA CELL INC. | 2018-11-08 | — | — | US | disclosed |
| US-20160097037-A1 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | GAMIDA CELL LTD. | 2016-04-07 | — | — | US | disclosed |
| EP-2206773-B1 | Expansion of renewable stem cell populations | GAMIDA CELL LTD (IL) | 2012-07-11 | — | — | EP | disclosed |
| US-7955852-B2 | Expansion of renewable stem cell populations | GAMIDA CELL LTD. (IL) | 2011-06-07 | — | — | US | disclosed |
| EP-2305794-A1 | Expansion of renewable stem cell populations | Gamida Cell Ltd. (IL) | 2011-04-06 | — | — | EP | disclosed |
| US-20110033427-A1 | Expansion Of Renewable Stem Cell Populations | GAMIDA CELL LTD. (IL) | 2011-02-10 | — | — | US | disclosed |
| EP-2206773-A1 | Espansion of renewable stem cell populations | Gamida Cell Ltd. (IL) | 2010-07-14 | — | — | EP | disclosed |
| EP-1576089-B1 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | GAMIDA CELL LTD (IL) | 2010-04-14 | — | — | EP | disclosed |
| EP-1576089-A4 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | GAMIDA CELL LTD (IL) | 2007-02-14 | — | — | EP | disclosed |
| EP-1601759-A4 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING MODULATORS OF PI 3-KINASE | GAMIDA CELL LTD (IL) | 2007-02-14 | — | — | EP | disclosed |
| EP-1601759-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING MODULATORS OF PI 3-KINASE | Gamida Cell Ltd. (IL) | 2005-12-07 | — | — | EP | disclosed |
| EP-1601759-A3 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING MODULATORS OF PI 3-KINASE | Gamida Cell Ltd. (IL) | 2005-10-27 | — | — | EP | disclosed |
| EP-1576089-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | Gamida Cell Ltd. (IL) | 2005-09-21 | — | — | EP | disclosed |
| US-20050054103-A1 | Expansion of renewable stem cell populations using modulators of PI 3-kinase | GAMIDA CELL LTD. (IL) | 2005-03-10 | — | — | US | disclosed |
| US-20050008624-A1 | Expansion of renewable stem cell populations | GAMIDA CELL LTD. | 2005-01-13 | — | — | US | disclosed |
| WO-2004078917-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS USING MODULATORS OF PI 3-KINASE | GAMIDA-CELL LTD. (IL) | 2004-09-16 | — | — | WO | disclosed |
| WO-2003062369-A2 | EXPANSION OF RENEWABLE STEM CELL POPULATIONS | GAMIDA-CELL LTD. (IL) | 2003-07-31 | — | — | WO | disclosed |