Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | VDR | P11473 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | CDC25A | P30304 | 1/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24813610 | 0.89 | MAPT (0.80) | MAPTVDRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19988240 | 0.89 | VDR (0.60) | MAPTVDRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1140730 | 0.88 | VDR (0.67) | MAPTVDRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1140731 | 0.88 | VDR (0.67) | MAPTVDRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11977559 | 0.88 | MAPT (0.80) | MAPTVDRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21128778 | 0.88 | MAPT (0.80) | MAPTVDRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25753376 | 0.88 | MAPT (0.80) | MAPTVDRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL21264751 | 0.88 | MAPT (0.80) | MAPTVDRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL12372105 | 0.88 | MAPT (0.80) | MAPTVDRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25753325 | 0.88 | MAPT (0.80) | MAPTVDRMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160144049-A1 | CARRIERS FOR IMPROVED DRUG DELIVERY | EXTEND BIOSCIENCES, INC. (US) | 2016-05-26 | — | — | US | disclosed |
| US-9289507-B2 | Carriers for improved drug delivery | EXTEND BIOSCIENCES, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150104469-A1 | CARRIERS FOR IMPROVED DRUG DELIVERY | EXTEND BIOSCIENCES, INC. (US) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150104469-A1 | CARRIERS FOR IMPROVED DRUG DELIVERY | GC, VDR, CYP24A1 | MAPT 1180/4885VDR 2/4885MEN1 2425/4885 |
| US-20160144049-A1 | CARRIERS FOR IMPROVED DRUG DELIVERY | GC, VDR, CYP24A1 | MAPT 1180/4885VDR 2/4885MEN1 2425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.