Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 12/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407323 | 1.00 | LMNA (0.62) | LMNAKDM4EMAPTOPRK1HTT | |
| SCHEMBL5708960 | 0.79 | TDP1 (0.67) | LMNAKDM4EMAPTOPRK1HTT | |
| SCHEMBL5708957 | 0.79 | TDP1 (0.67) | LMNAKDM4EMAPTOPRK1HTT | |
| SCHEMBL284105 | 0.77 | L3MBTL1 (1.00) | LMNAKDM4EMAPTOPRK1HTT | |
| SCHEMBL31621738 | 0.77 | L3MBTL1 (1.00) | LMNAKDM4EMAPTOPRK1HTT | |
| SCHEMBL284106 | 0.77 | L3MBTL1 (1.00) | LMNAKDM4EMAPTOPRK1HTT | |
| SCHEMBL4891420 | 0.76 | KDM4E (0.55) | LMNAKDM4EMAPTOPRK1HTT | |
| SCHEMBL4891424 | 0.76 | KDM4E (0.55) | LMNAKDM4EMAPTOPRK1HTT | |
| SCHEMBL29074605 | 0.76 | NQO2 (0.50) | LMNAKDM4EMAPTTDP1L3MBTL1 | |
| SCHEMBL21686429 | 0.75 | PHLPP2 (0.61) | LMNAKDM4EMAPTOPRK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204928-A | Photopolymerizable composition stabilized with nitrogen-containing aromatic compounds | STAUFFER CHEMICAL COMPANY (US) | 1980-05-27 | — | — | US | disclosed |
| US-4141807-A | ADDITION POLYMERS, QUINOLINE OR NAPHTHOL DERIVATIVES | STAUFFER CHEMICAL COMPANY (US) | 1979-02-27 | — | — | US | disclosed |