Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 10/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10550219 | 0.87 | NAAA (0.37) | CTSLNAAAGAAL3MBTL1MAPT | |
| SCHEMBL10680087 | 0.86 | NAAA (0.36) | CTSLNAAAGAAL3MBTL1MAPT | |
| SCHEMBL11397441 | 0.86 | CTSL (0.35) | CTSLNAAAGAAL3MBTL1MAPT | |
| SCHEMBL10553603 | 0.85 | NAAA (0.35) | CTSLNAAAGAAL3MBTL1MAPT | |
| SCHEMBL10546010 | 0.83 | NAAA (0.45) | NAAAGAAL3MBTL1ASAH1 | |
| SCHEMBL10545391 | 0.80 | MAPT (0.43) | CTSLNAAAMAPTPDE3ASLC22A6 | |
| SCHEMBL10546313 | 0.80 | TDP1 (0.33) | CTSLNAAAMAPTPDE3ASLC22A6 | |
| SCHEMBL10543551 | 0.80 | GAA (0.35) | CTSLGAAL3MBTL1MAPTPDE3A | |
| SCHEMBL10695608 | 0.80 | MEN1 (0.46) | CTSLNAAAMAPTPDE3ASLC22A6 | |
| SCHEMBL10543353 | 0.79 | TDP1 (0.35) | CTSLNAAAGAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |