Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | KLK1 | P06870 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.44 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 11/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | ADGRF1 | Q5T601 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415715 | 0.91 | ACHE (0.40) | F2KLK1PRSS1SLC22A2TMPRSS2 | |
| SCHEMBL11408296 | 0.87 | ACHE (0.42) | F2KLK1PRSS1SLC22A2TMPRSS2 | |
| SCHEMBL11417878 | 0.86 | F2 (0.42) | F2KLK1PRSS1SLC22A2TMPRSS2 | |
| SCHEMBL11415709 | 0.85 | ACHE (0.40) | ACHEC5AR1GPR183ADGRF1GPR65 | |
| SCHEMBL11410705 | 0.82 | F2 (0.44) | F2KLK1PRSS1SLC22A2TMPRSS2 | |
| SCHEMBL11414907 | 0.81 | CYP4F2 (0.41) | F2ACHEALDH1A1 | |
| SCHEMBL11415712 | 0.79 | PPARG (0.45) | ACHEC5AR1GPR183ADGRF1GPR65 | |
| SCHEMBL11410813 | 0.78 | ACHE (0.44) | ACHEC5AR1GPR183ADGRF1GPR65 | |
| SCHEMBL11408975 | 0.78 | ACHE (0.44) | ACHEC5AR1ALDH1A1 | |
| SCHEMBL11414455 | 0.78 | LMNA (0.47) | PRSS1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4214093-A | PROTEOLYTIC ENZYME INHIBITORS | TORII & CO., LTD. (JP) | 1980-07-22 | — | — | US | claimed |