Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1966472 | 0.82 | GLA (0.40) | ADORA3MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL9555439 | 0.79 | MAPT (0.35) | ADORA3MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL4742842 | 0.79 | MAPT (0.35) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL7088421 | 0.74 | KDM1A (0.36) | MEN1KMT2AMAPTALDH1A1RAB9A | |
| SCHEMBL30052413 | 0.73 | TRPA1 (0.35) | KDM4EMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL31172515 | 0.69 | NPC1 (0.36) | ADORA3MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8058925 | 0.69 | KDM1A (0.32) | MEN1KMT2AKDM4EMAPTLMNA | |
| SCHEMBL27919393 | 0.68 | MAPT (0.37) | ADORA3MEN1KMT2AKDM4EL3MBTL1 | |
| SCHEMBL5565774 | 0.68 | KDM1A (0.33) | MEN1KMT2AMAPTRAB9ALMNA | |
| SCHEMBL30874319 | 0.68 | KDM1A (0.38) | MEN1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4181655-A | ANTIDEPRESSANTS | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1980-01-01 | — | — | US | disclosed |