Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11409395 | 1.00 | CA1 (0.62) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL11411393 | 0.87 | CA1 (0.65) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL11411395 | 0.87 | CA1 (0.65) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL11418820 | 0.84 | CA1 (0.62) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL11418821 | 0.84 | CA1 (0.62) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL11418985 | 0.84 | CA1 (0.58) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL11418984 | 0.84 | CA1 (0.58) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL13934092 | 0.79 | CA2 (0.88) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL3129369 | 0.78 | CA2 (0.88) | CA1CA2PTGS2PTGS1ALDH1A1 | |
| SCHEMBL3129364 | 0.78 | CA2 (0.88) | CA1CA2PTGS2PTGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |