Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559698 | 0.88 | MAPT (0.38) | MAPTRAB9ACYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL8948248 | 0.79 | MAPT (0.43) | MAPTRAB9ACYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL3628526 | 0.78 | ALDH1A1 (0.42) | MAPTRAB9ACYP3A4ALDH1A1L3MBTL1 | |
| Hydrogen Sulfide SCHEMBL28258698 | 0.77 | ALDH1A1 (0.41) | MAPTRAB9ACYP3A4ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL28165709 | 0.75 | ALDH1A1 (0.40) | MAPTRAB9ACYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL8445226 | 0.73 | MTNR1A (0.45) | MAPTRAB9AALDH1A1CYP2C19CA12 | |
| SCHEMBL28165707 | 0.72 | ALDH1A1 (0.38) | MAPTRAB9ACYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL21480319 | 0.70 | MAPT (0.46) | MAPTRAB9ACYP3A4ALDH1A1L3MBTL1 | |
| Butane SCHEMBL10456574 | 0.69 | ALDH1A1 (0.42) | MAPTRAB9ACYP3A4ALDH1A1L3MBTL1 | |
| Butane SCHEMBL2511845 | 0.68 | MAPT (0.61) | MAPTCYP3A4ALDH1A1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239708-A | P-Phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters as anthelmentic agents | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| US-4137310-A | LARVICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-01-30 | — | — | US | disclosed |