SCHEMBL11409458

SCHEMBL11409458

COC(=O)c1cc(C(C)(C)C)c(OP(OC(=O)c2ccccc2)Oc2c(C(C)(C)C)cc(C(=O)OC)cc2C(C)(C)C)c(C(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
TNFRSF1A P19438 1/20 0.42
HPGD P15428 2/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 6/20 0.39
MAPT P10636 4/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
ALDH1A1 P00352 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
NPC1 O15118 3/20 0.38
PTPN1 P18031 1/20 0.38
AGTR1 P30556 1/20 0.38
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 1/20 0.38
PPARA Q07869 1/20 0.38
SLC6A3 Q01959 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11293485 0.82 TSHR (0.46) TSHRTNFRSF1AHPGDLMNARAB9A
SCHEMBL11522243 0.81 HPGD (0.52) TSHRTNFRSF1AHPGDLMNARAB9A
SCHEMBL11404448 0.80 CA1 (0.36) TSHRTNFRSF1AHPGDLMNAL3MBTL1
SCHEMBL10790658 0.76 CA12 (0.46) TSHRTNFRSF1AHPGDLMNAMAPT
SCHEMBL11403846 0.76 CA12 (0.42) TSHRTNFRSF1AHPGDLMNAMAPT
SCHEMBL5677096 0.73 TNFRSF1A (0.51) TSHRTNFRSF1ALMNAL3MBTL1ALDH1A1
SCHEMBL4143509 0.73 TNFRSF1A (0.37) TSHRTNFRSF1AHPGDLMNARAB9A
SCHEMBL11402026 0.71 THRA (0.40)
Methyl Benzoate SCHEMBL7200 0.71 TSHR (1.00) TSHRHPGDLMNARAB9AMAPT
Methyl Benzoate SCHEMBL1867855 0.71 TSHR (1.00) TSHRHPGDLMNARAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4207229-A STABILIZING POLYPROPYLENE AGAINST THERNAL, OXIDATIVE AND ULTRAVIOLET LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1980-06-10 US disclosed
US-4195016-A STABILIZERS OF POLYMERS AGAINST THERMAL, OXIDATIVE, AND ULTRAVIOLET LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1980-03-25 US disclosed
US-4182704-A STABILIZERS CIBA-GEIGY CORPORATION (US) 1980-01-08 US disclosed
US-4180498-A STABILIZERS OF POLYMERS AGAINST THERMAL, OXIDATIVE, AND ULTRAVIOLET LIGHT DEGRADATION CIBA-GEIGY CORPORATION (US) 1979-12-25 US disclosed
US-4094855-A Hindered phenyl phosphites CIBA-GEIGY CORPORATION (US) 1978-06-13 US disclosed