Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11409458 | 0.81 | TSHR (0.50) | HPGDLMNATNFRSF1ATSHRCA1 | |
| SCHEMBL11293485 | 0.79 | TSHR (0.46) | HPGDLMNATNFRSF1ATSHRCA1 | |
| SCHEMBL1406357 | 0.78 | LMNA (0.62) | HPGDLMNATNFRSF1ATSHRRXRA | |
| SCHEMBL11402026 | 0.76 | THRA (0.40) | — | |
| SCHEMBL11404448 | 0.74 | CA1 (0.36) | HPGDLMNATNFRSF1ATSHRCA1 | |
| SCHEMBL1406772 | 0.74 | LMNA (0.56) | HPGDLMNATSHRRXRARXRB | |
| SCHEMBL5364510 | 0.73 | RXRA (0.60) | HPGDLMNARXRARXRBRXRG | |
| SCHEMBL10790658 | 0.73 | CA12 (0.46) | HPGDLMNATNFRSF1ATSHRCA1 | |
| SCHEMBL11403846 | 0.73 | CA12 (0.42) | HPGDLMNATNFRSF1ATSHRCA1 | |
| SCHEMBL5677096 | 0.70 | TNFRSF1A (0.51) | LMNATNFRSF1ATSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4180497-A | STABILIZERS FOR ORGANIC POLYMERS AGAINST THERMAL, OXIDATIVE AND UV LIGHT DEGRADATION | CIBA-GEIGY CORPORATION (US) | 1979-12-25 | — | — | US | disclosed |