Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463756 | 0.80 | SLC22A6 (0.39) | ERN1KEAP1CYP1A2CA1CA2 | |
| SCHEMBL9987590 | 0.76 | CA1 (0.32) | CA1CA2CA9 | |
| SCHEMBL311749 | 0.73 | ALDH1A1 (0.42) | ERN1KEAP1MAPTCYP1A2CYP2C9 | |
| SCHEMBL1253062 | 0.71 | ALDH1A1 (0.41) | ERN1KEAP1MAPTCYP1A2CYP2C9 | |
| SCHEMBL221122 | 0.70 | MAPT (0.44) | MAPTCYP1A2CYP2C19RAB9ASMN1; SMN2 | |
| SCHEMBL20507058 | 0.69 | ALDH1A1 (0.34) | KEAP1CA1CA2TDP1ALDH1A1 | |
| SCHEMBL10953256 | 0.69 | MAPT (0.43) | ERN1KEAP1MAPTCYP1A2CYP2C9 | |
| SCHEMBL8129922 | 0.67 | MAPT (0.41) | MAPTRAB9ATDP1ALDH1A1CYP2A6 | |
| SCHEMBL8890037 | 0.67 | KEAP1 (0.42) | KEAP1CYP1A2CA1CA2CA9 | |
| SCHEMBL15412117 | 0.67 | SLC2A1 (0.35) | MAPTL3MBTL1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239755-A | SLOW RELEASE IN VIVO OF ACTIVE STEROIDS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1980-12-16 | — | — | US | disclosed |
| US-4203864-A | DISSOLVING A CONDENSED PHOSPHATE IN WATER; ADDING UREA, SOLID PARTICLES AND THEN AND ANTIFREEZE SOLUTION | INTERNATIONAL TELEPHONE AND TELEGRAPH CORPORATION (US) | 1980-05-20 | — | — | US | disclosed |