Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11409601 | 1.00 | MAPT (0.42) | MAPTALDH1A1KDM4ESIRT2KMT2A | |
| SCHEMBL11411127 | 0.85 | SIRT2 (0.46) | MAPTALDH1A1KDM4ESIRT2KMT2A | |
| SCHEMBL11411120 | 0.85 | SIRT2 (0.46) | MAPTALDH1A1KDM4ESIRT2KMT2A | |
| SCHEMBL11402906 | 0.82 | MAPT (0.39) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11402904 | 0.82 | MAPT (0.39) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11404101 | 0.79 | CA12 (0.40) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL11404098 | 0.79 | CA12 (0.40) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL5449980 | 0.78 | NFE2L2 (0.50) | MAPTALDH1A1KDM4ESIRT2KMT2A | |
| SCHEMBL9304452 | 0.78 | NFE2L2 (0.50) | MAPTALDH1A1KDM4ESIRT2KMT2A | |
| SCHEMBL28613801 | 0.78 | NFE2L2 (0.50) | MAPTALDH1A1KDM4ESIRT2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224340-A | Anti-inflammatory compositions containing α-phenyl-N-phenylnitrone compounds | WILLIAM H. RORER, INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4214003-A | ANTIINFLAMMATORY AGENTS | WILLIAM H. RORER, INC. (US) | 1980-07-22 | — | — | US | disclosed |
| US-4197314-A | WITH A DIPHENYL NITRONE | WILLIAM H. RORER, INC. (US) | 1980-04-08 | — | — | US | disclosed |
| US-4153722-A | ANTIINFLAMMATORY, A-PHENYL-N-PHENYLNITRONE | WILLIAM H. RORER, INC. (US) | 1979-05-08 | — | — | US | disclosed |