Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11409711 | 1.00 | PTPN1 (0.46) | PTPN1HNF4APTGS1PTGS2ALDH1A1 | |
| SCHEMBL11423226 | 0.84 | ALDH1A1 (0.45) | PTPN1HNF4APTGS1PTGS2ALDH1A1 | |
| SCHEMBL11423177 | 0.84 | ALDH1A1 (0.45) | PTPN1HNF4APTGS1PTGS2ALDH1A1 | |
| SCHEMBL11423175 | 0.84 | ALDH1A1 (0.45) | PTPN1HNF4APTGS1PTGS2ALDH1A1 | |
| SCHEMBL11423229 | 0.84 | ALDH1A1 (0.45) | PTPN1HNF4APTGS1PTGS2ALDH1A1 | |
| SCHEMBL11429663 | 0.78 | TSHR (0.55) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL11429665 | 0.78 | TSHR (0.55) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL14982912 | 0.78 | CA12 (0.57) | ALDH1A1KDM4EHPGDSMN1; SMN2LMNA | |
| SCHEMBL11407450 | 0.77 | POLB (0.57) | PTGS1PTGS2ALDH1A1KDM4EHPGD | |
| SCHEMBL11407451 | 0.77 | POLB (0.57) | PTGS1PTGS2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |