Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.45 |
| ▸ | HPGD | P15428 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423175 | 1.00 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL11409711 | 0.84 | PTPN1 (0.46) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL11409709 | 0.84 | PTPN1 (0.46) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL11423226 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL11423229 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL11409847 | 0.80 | DHODH (0.64) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL11409867 | 0.79 | DHODH (0.48) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL11409879 | 0.79 | DHODH (0.48) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL11416848 | 0.77 | DHODH (0.44) | ALDH1A1KDM4EHPGDLMNAKMT2A | |
| SCHEMBL11416851 | 0.77 | DHODH (0.44) | ALDH1A1KDM4EHPGDLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |