Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11413647 | 0.80 | CA12 (0.46) | PBRM1CA2CA9CA12MAPT | |
| SCHEMBL11413649 | 0.80 | CA12 (0.46) | PBRM1CA2CA9CA12MAPT | |
| SCHEMBL11414965 | 0.77 | CA12 (0.38) | PTGS2PBRM1CA2CA9CA12 | |
| SCHEMBL11410987 | 0.73 | CA2 (0.47) | PTGS2CA2CA9CA12MAPT | |
| SCHEMBL11411127 | 0.73 | SIRT2 (0.46) | PTGS2CA2CA9MAPTCA1 | |
| SCHEMBL11411120 | 0.73 | SIRT2 (0.46) | PTGS2CA2CA9MAPTCA1 | |
| SCHEMBL11415876 | 0.73 | MAPT (0.53) | SPHK2SPHK1CA2CA9CA12 | |
| SCHEMBL11415897 | 0.73 | MAPT (0.53) | SPHK2SPHK1CA2CA9CA12 | |
| SCHEMBL11406095 | 0.72 | PTGS2 (0.50) | PTGS2PBRM1CA2CA9CA12 | |
| SCHEMBL11406096 | 0.72 | PTGS2 (0.50) | PTGS2PBRM1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230727-A | N-BENZYLIDENEANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4187317-A | Sunscreen and erythema treating with N-benzylidene anilenes | WILLIAM H. RORER, INC. (US) | 1980-02-05 | — | — | US | disclosed |