Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11410309 | 0.75 | KMT2A (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8820811 | 0.73 | SMN1; SMN2 (0.76) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL16071443 | 0.73 | EPHX1 (0.76) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29886123 | 0.72 | MAPT (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3102961 | 0.72 | MAPT (0.67) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL3532051 | 0.71 | MAPT (0.65) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14409744 | 0.71 | NR1H4 (0.62) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL17762698 | 0.71 | SMN1; SMN2 (0.75) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12355553 | 0.71 | SMN1; SMN2 (0.75) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL527994 | 0.70 | RAB9A (0.77) | KMT2AMEN1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224025-A | Process for the dyeing and printing of paper materials in different hues using a single coupling component | CIBA-GEIGY CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4168952-A | ACETOACETIC ACID ARYLAMIDE AS COUPLER | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-09-25 | — | — | US | disclosed |
| US-4165967-A | HYDROXY-PYRIDINE OR PYRIDONE COUPLERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1979-08-28 | — | — | US | disclosed |
| US-4162893-A | Process for dyeing human hair with diazo salts | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1979-07-31 | — | — | US | disclosed |
| US-4065254-A | DIAZO DYES, LEATHER, COTTON, WOOL | CIBA-GEIGY CORPORATION (US) | 1977-12-27 | — | — | US | disclosed |