SCHEMBL527994

SCHEMBL527994

COc1ccccc1NC(=O)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.77
NPC1 O15118 1/20 0.77
PABPC1 P11940 1/20 0.72
APOBEC3A P31941 1/20 0.72
EIF4H Q15056 1/20 0.72
APOBEC3G Q9HC16 1/20 0.72
MAPT P10636 1/20 0.70
MLYCD O95822 1/20 0.70
KMT2A Q03164 6/20 0.69
MEN1 O00255 5/20 0.67
PKM P14618 1/20 0.67
HDAC1 Q13547 1/20 0.66
HDAC8 Q9BY41 1/20 0.66
HDAC6 Q9UBN7 1/20 0.66
AHR P35869 1/20 0.66
P4HTM Q9NXG6 1/20 0.65
HPGD P15428 2/20 0.65
ALDH1A1 P00352 1/20 0.65
HTT P42858 1/20 0.65
KDM4E B2RXH2 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29989592 1.00 RAB9A (0.77) RAB9ANPC1PABPC1APOBEC3AEIF4H
SCHEMBL28185207 0.92 NPC1 (0.67) RAB9ANPC1PABPC1APOBEC3AEIF4H
SCHEMBL16583906 0.92 RAB9A (0.70) RAB9ANPC1PABPC1APOBEC3AEIF4H
SCHEMBL16681360 0.89 KMT2A (0.76) RAB9ANPC1PABPC1APOBEC3AEIF4H
SCHEMBL9620772 0.88 F10 (0.81) RAB9ANPC1PABPC1APOBEC3AEIF4H
SCHEMBL8970971 0.88 POLB (0.70) RAB9ANPC1PABPC1APOBEC3AEIF4H
SCHEMBL9620767 0.88 MLYCD (0.69) RAB9ANPC1PABPC1APOBEC3AEIF4H
SCHEMBL8874149 0.87 NAMPT (0.62) RAB9ANPC1PABPC1APOBEC3AEIF4H
SCHEMBL96146 0.87 MLYCD (0.68) RAB9ANPC1PABPC1APOBEC3AEIF4H
SCHEMBL682871 0.87 GAA (0.68) RAB9ANPC1PABPC1APOBEC3AEIF4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580404-A2 SULFONAMIDE APYRASE INHIBITORS Texas Crop Science, Inc. (US) 2025-07-09 EP claimed
US-20240099300-A1 SULFONAMIDE APYRASE INHIBITORS TEXAS CROP SCIENCE, INC. 2024-03-28 US claimed
WO-2024050041-A2 SULFONAMIDE APYRASE INHIBITORS TEXAS CROP SCIENCE (US) 2024-03-07 WO claimed
WO-2012014127-A1 5-LIPOXYGENASE INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2012-02-02 WO claimed
EP-1751136-A2 NITROGENATED HETEROCYCLIC DERIVATIVES AS PROTEIN KINASE MODULATORS AND USE FOR THE TREATMENT OF ANGIOGENESIS AND CANCER AMGEN INC. (US) 2007-02-14 EP claimed
WO-2005113494-A2 NITROGENATED HETEROCYCLIC DERIVATIVES AS PROTEIN KINASE MODULATORS AND USE FOR THE TREATMENT OF ANGIOGENESIS AND CANCER AMGEN INC. (US) 2005-12-01 WO claimed
EP-0775110-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1997-05-28 EP claimed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
WO-1996004242-A1 ARYLTHIO COMPOUNDS AS ANTIBACTERIAL AND ANTIVIRAL AGENTS WARNER-LAMBERT COMPANY (US) 1996-02-15 WO claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
US-20240099300-A1 SULFONAMIDE APYRASE INHIBITORS TEXAS CROP SCIENCE, INC. 2024-03-28 US disclosed
CN-112898173-B Method for preparing amide compound by photocatalytic organic amine 湖南中医药大学 2022-10-11 CN disclosed
CN-112898173-A Method for preparing amide compound by photocatalytic organic amine 湖南中医药大学 2021-06-04 CN disclosed
WO-2002085838-A1 COPPER-CATALYZED FORMATION OF CARBON-HETEROATOM AND CARBON-CARBON BONDS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2002-10-31 WO disclosed
US-20020156281-A1 Amide inhibitors of microsomal triglyceride transfer protein BOOTH RICHARD JOHN (US) 2002-10-24 US disclosed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP disclosed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US disclosed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020156281-A1 Amide inhibitors of microsomal triglyceride transfer protein CETP, MTTP, LCAT RAB9A 2995/4885NPC1 35/4885PABPC1 2960/4885
US-20240099300-A1 SULFONAMIDE APYRASE INHIBITORS APEH, ARSA, DNPEP RAB9A 1777/4885NPC1 3337/4885PABPC1 2795/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.