Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | POLH | Q9Y253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4165238 | 0.81 | APP (0.46) | EPHX2APPPOLHKDM4EMEN1 | |
| SCHEMBL4157261 | 0.76 | SRC (0.44) | EPHX2APPPOLHKDM4EMEN1 | |
| SCHEMBL4169452 | 0.73 | ALOX5 (0.49) | POLHALOX5 | |
| SCHEMBL4152750 | 0.73 | ALOX5 (0.50) | POLHALOX5 | |
| SCHEMBL4158688 | 0.73 | ALOX5 (0.50) | POLHALOX5 | |
| SCHEMBL4164333 | 0.73 | ALOX5 (0.50) | POLHALOX5 | |
| SCHEMBL4165925 | 0.73 | ALOX5 (0.50) | POLHALOX5 | |
| SCHEMBL4155997 | 0.73 | ALOX5 (0.50) | POLHALOX5 | |
| SCHEMBL16949822 | 0.68 | APP (0.62) | APPPOLHKDM4EMEN1MAPT | |
| SCHEMBL23442263 | 0.67 | EPHX2 (0.79) | EPHX2APPPOLHKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55111418-A | — | — | None | — | — | JP | disclosed |
| JP-S55111418-A | REMEDY FOR EYE DISEASE AND ITS PREPARATION | SANTEN PHARMACEUT CO LTD | 1980-08-28 | — | — | JP | disclosed |