Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11412348 | 1.00 | CA2 (0.51) | CA2CA1LMNACYP1A2CYP2C9 | |
| SCHEMBL11415296 | 0.85 | CYP1A2 (0.54) | CA2CA1LMNACYP1A2CYP2C9 | |
| SCHEMBL11410869 | 0.85 | CYP1A2 (0.54) | CA2CA1LMNACYP1A2CYP2C9 | |
| SCHEMBL11415378 | 0.84 | PTGS2 (0.50) | CA2CA1LMNACYP1A2CYP2C9 | |
| SCHEMBL11415375 | 0.84 | PTGS2 (0.50) | CA2CA1LMNACYP1A2CYP2C9 | |
| SCHEMBL12416605 | 0.81 | SIRT2 (0.71) | CA2CA1LMNATSHRSIRT2 | |
| SCHEMBL11415370 | 0.81 | CYP1A2 (0.48) | CA2CA1LMNACYP1A2CYP2C9 | |
| SCHEMBL11415373 | 0.81 | CYP1A2 (0.48) | CA2CA1LMNACYP1A2CYP2C9 | |
| SCHEMBL12416792 | 0.80 | MAPT (0.47) | CA2CA1LMNASIRT2ALDH1A1 | |
| SCHEMBL16589424 | 0.79 | CA2 (0.74) | CA2CA1LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55149255-A | — | — | None | — | — | JP | disclosed |
| JP-S55149255-A | PREPARATION OF NOVEL 4-(1-OXO-2-ISOINDOLINYL)ACETOPHENONE | HISAMITSU PHARMACEUT CO INC | 1980-11-20 | — | — | JP | disclosed |