Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | EPAS1 | Q99814 | 9/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058774 | 0.81 | PTGS1 (0.46) | MEN1KMT2AALDH1A1HSD17B3HSD17B2 | |
| SCHEMBL16555813 | 0.79 | EPAS1 (0.56) | MEN1KMT2AALDH1A1EPAS1PTGS1 | |
| SCHEMBL11882785 | 0.79 | HSD17B3 (0.50) | HSD17B3HSD17B2PTGS1PTGS2CA2 | |
| SCHEMBL68932 | 0.78 | GAA (0.57) | ALDH1A1HSD17B3HSD17B2PTGS1PTGS2 | |
| SCHEMBL29598983 | 0.78 | GAA (0.57) | ALDH1A1HSD17B3HSD17B2PTGS1PTGS2 | |
| SCHEMBL9341624 | 0.78 | GAA (0.57) | ALDH1A1HSD17B3HSD17B2PTGS1PTGS2 | |
| SCHEMBL21728893 | 0.78 | MEN1 (0.53) | MEN1KMT2AALDH1A1EPAS1PTGS1 | |
| SCHEMBL1881348 | 0.78 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1EPAS1CA2 | |
| SCHEMBL11409224 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1EPAS1P2RX1 | |
| SCHEMBL3021489 | 0.78 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1P2RX1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4195082-A | Combating arthropods with 0-alkyl-0-trifluoromethylsulphonylphenyl-thiono (thiol)-phosphoric acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1980-03-25 | — | — | US | disclosed |