Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EPAS1 | Q99814 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14453589 | 0.85 | MEN1 (0.56) | MEN1KMT2AEPAS1ALDH1A1POLB | |
| SCHEMBL21983964 | 0.82 | LMNA (0.55) | MEN1KMT2AEPAS1ALDH1A1POLB | |
| SCHEMBL16555813 | 0.79 | EPAS1 (0.56) | MEN1KMT2AEPAS1ALDH1A1PTGS2 | |
| SCHEMBL29217918 | 0.79 | ALDH1A1 (0.52) | MEN1KMT2AEPAS1ALDH1A1POLB | |
| SCHEMBL29957896 | 0.79 | POLB (0.48) | MEN1KMT2AEPAS1ALDH1A1POLB | |
| SCHEMBL12537977 | 0.79 | POLB (0.48) | MEN1KMT2AEPAS1ALDH1A1POLB | |
| SCHEMBL5936707 | 0.78 | LMNA (0.50) | ALDH1A1POLBPTGS2PTGS1LMNA | |
| SCHEMBL24456745 | 0.78 | EPAS1 (0.59) | MEN1KMT2AEPAS1ALDH1A1POLB | |
| SCHEMBL1881348 | 0.78 | ALDH1A1 (0.70) | MEN1KMT2AEPAS1ALDH1A1POLB | |
| SCHEMBL13556573 | 0.78 | ALDH1A1 (0.70) | MEN1KMT2AEPAS1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773616-B1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-02-19 | — | — | EP | disclosed |