SCHEMBL11413403

SCHEMBL11413403

CCC1(C)CC(O[Si](OC2CC(C)(CC)N(C(C)=O)C(C)(CC)C2C)(c2ccccc2)c2ccccc2)C(C)C(C)(CC)N1C(C)=O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
OPRM1 P35372 3/20 0.31
OPRD1 P41143 3/20 0.31
OPRK1 P41145 3/20 0.31
GAA P10253 1/20 0.31
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11413341 0.91 ALDH1A1 (0.32) ALDH1A1LMNAL3MBTL1OPRM1OPRD1
SCHEMBL11413269 0.91 ALDH1A1 (0.34) ALDH1A1LMNAL3MBTL1OPRM1OPRD1
SCHEMBL11415212 0.90 ALDH1A1 (0.32) ALDH1A1LMNAL3MBTL1OPRM1OPRD1
SCHEMBL11412517 0.90 ALDH1A1 (0.32) ALDH1A1LMNAL3MBTL1OPRM1OPRD1
SCHEMBL11422482 0.82 LMNA (0.31) ALDH1A1LMNAOPRM1OPRD1OPRK1
SCHEMBL11533829 0.81 TSHR (0.44) LMNAL3MBTL1GAA
SCHEMBL11412226 0.81 ALDH1A1 (0.32) ALDH1A1LMNAL3MBTL1OPRM1OPRD1
SCHEMBL11422605 0.78
SCHEMBL11452286 0.74 TDP1 (0.43) ALDH1A1LMNAL3MBTL1KDM4E
SCHEMBL11527304 0.72 KMT2A (0.42) ALDH1A1LMNAL3MBTL1GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4210578-A LIGHT-STABILIZERS FOR PLASTICS CIBA-GEIGY CORPORATION (US) 1980-07-01 US disclosed