Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884859 | 0.90 | TSHR (0.48) | TSHRTDP1PRSS1NPC1RECQL | |
| SCHEMBL8944334 | 0.86 | S1PR4 (0.43) | TSHRTDP1PRSS1NPC1RECQL | |
| SCHEMBL12047595 | 0.83 | PRSS1 (0.46) | TSHRTDP1PRSS1NPC1RECQL | |
| SCHEMBL9024000 | 0.83 | KDM4E (0.41) | TSHRTDP1PRSS1NPC1RECQL | |
| SCHEMBL28909989 | 0.82 | PTGES (0.45) | TSHRTDP1PRSS1NPC1RECQL | |
| SCHEMBL29538190 | 0.82 | PTGES (0.45) | TSHRTDP1PRSS1NPC1RECQL | |
| SCHEMBL10887600 | 0.82 | CHEK1 (0.50) | TSHRTDP1PRSS1NPC1RAB9A | |
| SCHEMBL10885884 | 0.82 | MERTK (0.46) | TSHRTDP1PRSS1NPC1RECQL | |
| SCHEMBL9865389 | 0.81 | SNCA (0.44) | TSHRTDP1PRSS1NPC1RECQL | |
| SCHEMBL28654265 | 0.80 | MEN1 (0.57) | TSHRALDH1A1MAPTGPR35MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4201853-A | FOR PLASTIC BONDED EXPLOSIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1980-05-06 | — | — | US | disclosed |