Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL8944344 | 0.91 | NPC1 (0.42) | S1PR4TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL11414367 | 0.86 | TSHR (0.43) | TDP1TSHRALDH1A1PRSS1NPC1 | |
| SCHEMBL10885884 | 0.84 | MERTK (0.46) | S1PR4TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL6815549 | 0.82 | MAPT (0.49) | S1PR4TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL10884859 | 0.82 | TSHR (0.48) | S1PR4TDP1TSHRALDH1A1PRSS1 | |
| SCHEMBL6814271 | 0.79 | MAPT (0.47) | S1PR4ALDH1A1CYP3A4NPC1RAB9A | |
| SCHEMBL9024000 | 0.79 | KDM4E (0.41) | S1PR4TDP1TSHRALDH1A1PRSS1 | |
| SCHEMBL10928788 | 0.78 | S1PR4 (0.45) | S1PR4TDP1TSHRALDH1A1CYP3A4 | |
| SCHEMBL9865389 | 0.78 | SNCA (0.44) | TDP1TSHRALDH1A1CYP3A4PRSS1 | |
| SCHEMBL20305541 | 0.78 | DPP4 (0.53) | TDP1ALDH1A1CYP3A4DPP4PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331144-B1 | 3-SUBSTITUTED PARA-AMINO PHENOLS, PROCESS FOR THEIR PREPARATION, THEIR USE IN DYEING KERATENIC FIBRES AND INTERMEDIATES USED IN THE PREPARATION PROCESS | L'OREAL (FR) | 1993-06-09 | — | — | EP | claimed |
| US-5503640-A | ALKYLTHIO PARA-AMINOPHENOLS IN AQUEOUS VEHICLE FOR DYEING HUMAN HAIR | L'OREAL (FR) | 1996-04-02 | — | — | US | disclosed |
| US-5364413-A | Oxidation color dyes for hair | L'OREAL (FR) | 1994-11-15 | — | — | US | disclosed |
| US-5084067-A | Indoaniline dyes for hair dyes | L'OREAL (FR) | 1992-01-28 | — | — | US | disclosed |