SCHEMBL11414413

CSCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.65

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	15/20	0.65

▸	OPRM1	P35372	7/20	0.65

▸	OPRK1	P41145	1/20	0.65

▸	CCKAR	P32238	3/20	0.57

▸	CCKBR	P32239	3/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11497413	0.94	OPRD1 (0.74)	OPRD1OPRM1OPRK1CCKARCCKBR
SCHEMBL29351381	0.94	OPRD1 (0.74)	OPRD1OPRM1OPRK1CCKARCCKBR
Hydrochloric Acid SCHEMBL11235207	0.93	OPRD1 (0.73)	OPRD1OPRM1OPRK1CCKARCCKBR
SCHEMBL11414405	0.90	OPRD1 (0.60)	OPRD1OPRM1OPRK1CCKARCCKBR
SCHEMBL7206228	0.90	OPRD1 (0.65)	OPRD1OPRM1OPRK1CCKARCCKBR
SCHEMBL11496315	0.88	OPRD1 (0.73)	OPRD1OPRM1OPRK1CCKARCCKBR
SCHEMBL11680970	0.88	OPRD1 (0.75)	OPRD1OPRM1OPRK1
SCHEMBL29390218	0.88	OPRD1 (0.75)	OPRD1OPRM1OPRK1
Acetic Acid SCHEMBL2027936	0.88	OPRD1 (0.74)	OPRD1OPRM1OPRK1
Tyrlysseraspserphetyrglyleumet SCHEMBL30475005	0.87	OPRM1 (0.61)	OPRD1OPRM1OPRK1CCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0015274-A1	IMPROVED ENKEPHALIN DERIVATIVES	KASTIN, Abba J. (US)	1980-09-17	—	—	EP	disclosed
WO-1980000022-A1	IMPROVED ENKEPHALIN DERIVATIVES	KASTIN A (US)	1980-01-10	—	—	WO	disclosed