Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 17/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL113496 | 0.90 | CXCR3 (0.32) | CXCR3 | |
| SCHEMBL113908 | 0.82 | DGAT1 (0.36) | CXCR3KCNH2 | |
| SCHEMBL114031 | 0.81 | CXCR3 (0.35) | CXCR3 | |
| SCHEMBL114320 | 0.79 | ATR (0.32) | — | |
| SCHEMBL3726267 | 0.78 | CXCR3 (0.58) | CXCR3KCNH2 | |
| SCHEMBL112451 | 0.77 | CXCR3 (0.35) | CXCR3 | |
| SCHEMBL115742 | 0.75 | PIK3CA (0.33) | — | |
| SCHEMBL3724591 | 0.72 | CXCR3 (0.53) | CXCR3KCNH2 | |
| SCHEMBL160019 | 0.70 | CXCR3 (0.52) | CXCR3KCNH2 | |
| SCHEMBL3730855 | 0.70 | CXCR3 (0.58) | CXCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424840-A1 | CXCR3 RECEPTOR ANTAGONISTS | Boehringer Ingelheim International GmbH (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010126811-A1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-04 | — | — | WO | disclosed |