Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.47 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | CBX7 | O95931 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11405828 | 1.00 | SLC40A1 (0.47) | SLC40A1TIMP3MEN1KMT2ARECQL | |
| SCHEMBL11481702 | 0.88 | TIMP3 (0.50) | SLC40A1TIMP3MEN1KMT2ARECQL | |
| SCHEMBL11405673 | 0.86 | TIMP3 (0.48) | SLC40A1TIMP3MEN1KMT2ARECQL | |
| SCHEMBL11412735 | 0.85 | SLC40A1 (0.48) | SLC40A1MEN1KMT2ARECQLTDP1 | |
| SCHEMBL11411033 | 0.84 | TIMP3 (0.46) | TIMP3MEN1KMT2ARECQLTDP1 | |
| SCHEMBL11405798 | 0.83 | TIMP3 (0.47) | TIMP3MEN1KMT2ARECQLTDP1 | |
| SCHEMBL11411036 | 0.83 | TIMP3 (0.47) | TIMP3MEN1KMT2ARECQLTDP1 | |
| SCHEMBL11422060 | 0.82 | MEN1 (0.48) | TIMP3MEN1KMT2ARECQLTDP1 | |
| SCHEMBL11415488 | 0.82 | MEN1 (0.48) | TIMP3MEN1KMT2ARECQLTDP1 | |
| SCHEMBL11414900 | 0.82 | TIMP3 (0.46) | TIMP3MEN1KMT2ARECQLTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4231958-A | AMINOPHENYLENECARBONYL /AND SULFONYL/IMINONAPHTHALENE INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4229370-A | INHIBITORS OF THE COMPLEMENT SYSTEM, IMMUNOLOGY | AMERICAN CYANAMID COMPANY (US) | 1980-10-21 | — | — | US | disclosed |
| US-4155930-A | Ureylene phenylene anionic naphthalenesulfonic acids | AMERICAN CYANAMID COMPANY (US) | 1979-05-22 | — | — | US | disclosed |