SCHEMBL11414909

SCHEMBL11414909

CCCCOCC1(CO)COC1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
EPHX1 P07099 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.36
PRKCA P17252 2/20 0.35
MEN1 O00255 1/20 0.34
THRB P10828 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 1/20 0.34
ASGR1 P07306 3/20 0.34
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
USP2 O75604 1/20 0.31
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8308487 0.93 HTT (0.44) TSHREPHX1PRKCAMEN1THRB
SCHEMBL15129822 0.93 HTT (0.44) TSHREPHX1PRKCAMEN1THRB
SCHEMBL5945228 0.88 SMN1; SMN2 (0.41) TSHREPHX1SMN1; SMN2MEN1THRB
SCHEMBL124555 0.85 SMN1; SMN2 (0.38) TSHRSMN1; SMN2ASGR1LMNAPOLB
SCHEMBL3241659 0.84 TSHR (0.38) TSHREPHX1SMN1; SMN2PRKCAMEN1
SCHEMBL28774510 0.83 SMN1; SMN2 (0.37) TSHRSMN1; SMN2ASGR1LMNAPOLB
SCHEMBL28774515 0.83 SMN1; SMN2 (0.37) TSHRSMN1; SMN2ASGR1LMNAPOLB
SCHEMBL28774513 0.81 SMN1; SMN2 (0.36) TSHRSMN1; SMN2MEN1THRBHTT
SCHEMBL214598 0.81 TSHR (0.38) TSHRSMN1; SMN2MEN1THRBHTT
SCHEMBL16572523 0.81 SMN1; SMN2 (0.36) TSHRSMN1; SMN2ASGR1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2804763-B1 PLASTIC FILM FOR PRINTING BY MEANS OF DYE DIFFUSION THERMAL TRANSFER PRINTING COVESTRO DEUTSCHLAND AG (DE) 2018-05-02 EP disclosed
EP-2676965-B1 ARYL GLYCOSIDE COMPOUND, PREPARATION METHOD AND USE THEREOF SHANGHAI YINGLI PHARM CO LTD (CN) 2017-10-04 EP disclosed
US-9446619-B2 Plastic film for printing by dye diffusion thermal transfer printing COVESTRO DEUTSCHLAND AG (DE) 2016-09-20 US disclosed
US-9375968-B2 Plastic film for printing by dye diffusion thermal transfer printing COVESTRO DEUTSCHLAND AG (DE) 2016-06-28 US disclosed
US-8980829-B2 Aryl glycoside compound, preparation method and use thereof SHANGHAI YINGLI SCIENCE AND TECHNOLOGY CO., LTD (CN) 2015-03-17 US disclosed
US-20150004377-A1 PLASTIC FILM FOR PRINTING BY DYE DIFFUSION THERMAL TRANSFER PRINTING COVESTRO DEUTSCHLAND AG (DE) 2015-01-01 US disclosed
US-20140349038-A1 PLASTIC FILM FOR PRINTING BY DYE DIFFUSION THERMAL TRANSFER PRINTING COVESTRO DEUTSCHLAND AG (DE) 2014-11-27 US disclosed
EP-2804764-A1 PLASTIC FILM FOR PRINTING BY DYE DIFFUSION THERMAL TRANSFER PRINTING Bayer Intellectual Property GmbH (DE) 2014-11-26 EP disclosed
EP-2804763-A1 PLASTIC FILM FOR PRINTING BY DYE DIFFUSION THERMAL TRANSFER PRINTING Bayer Intellectual Property GmbH (DE) 2014-11-26 EP disclosed
WO-2013107777-A1 PLASTIC FILM FOR PRINTING BY DYE DIFFUSION THERMAL TRANSFER PRINTING BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-25 WO disclosed
WO-2013107773-A1 PLASTIC FILM FOR PRINTING BY DYE DIFFUSION THERMAL TRANSFER PRINTING BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-25 WO disclosed
US-4225483-A Boric acid esters and oxetanes for stabilizing phosphite-free polycarbonates BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed
EP-0001823-A2 Use of esters of boric acid to stabilize phosphite-free polycarbonates, and the obtained stabilized polycarbonate moulding compositions BAYER AG (DE) 1979-05-16 EP disclosed