Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15129822 | 1.00 | HTT (0.44) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL11414909 | 0.93 | TSHR (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL13423659 | 0.89 | ALDH1A1 (0.44) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL14256280 | 0.86 | ALDH1A1 (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL3164645 | 0.86 | ALDH1A1 (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10071379 | 0.86 | ALDH1A1 (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9933808 | 0.86 | ALDH1A1 (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL14256281 | 0.86 | ALDH1A1 (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL2902859 | 0.86 | ALDH1A1 (0.42) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL2623190 | 0.86 | ALDH1A1 (0.42) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607374-B1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | PO HANG IRON & STEEL (KR) | 1999-04-07 | — | — | EP | disclosed |
| US-5700817-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD. (KR) | 1997-12-23 | — | — | US | disclosed |
| US-5610310-A | Cyclic lipid derivatives as potent PAF antagonists | POHANG IRON & STEEL CO., LTD (KR) | 1997-03-11 | — | — | US | disclosed |
| EP-0607374-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-07-27 | — | — | EP | disclosed |
| WO-1994000447-A1 | NOVEL CYCLIC LIPID DERIVATIVES AS POTENT PAF ANTAGONISTS | POHANG IRON & STEEL CO., LTD. (KR) | 1994-01-06 | — | — | WO | disclosed |