Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.57 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | GNPAT | O15228 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 4/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5812584 | 1.00 | LAP3 (0.57) | LAP3ANPEPRNPEPDNPEPHDAC3 | |
| SCHEMBL5812579 | 1.00 | LAP3 (0.57) | LAP3ANPEPRNPEPDNPEPHDAC3 | |
| SCHEMBL21570273 | 0.92 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPHDAC3 | |
| SCHEMBL21570275 | 0.92 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPHDAC3 | |
| SCHEMBL5812534 | 0.92 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPHDAC3 | |
| SCHEMBL5812528 | 0.92 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPHDAC3 | |
| SCHEMBL13427297 | 0.90 | HDAC3 (0.55) | LAP3ANPEPRNPEPDNPEPHDAC3 | |
| SCHEMBL11414316 | 0.88 | MME (0.61) | LAP3ANPEPRNPEPDNPEPMME | |
| SCHEMBL11414321 | 0.88 | MME (0.61) | LAP3ANPEPRNPEPDNPEPMME | |
| SCHEMBL11412768 | 0.87 | NAALAD2 (0.63) | LAP3ANPEPRNPEPDNPEPMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4240975-A | USED AS ENZYME INHIBITOR, ANTIFERTILITY AGENT, AND ENHANCES THE ANTITUMOR EFFECT OF BLEOMYCIN | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1980-12-23 | — | — | US | disclosed |