Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.53 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415326 | 1.00 | TLR2 (0.53) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11410278 | 0.89 | TLR2 (0.55) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11404742 | 0.89 | TLR2 (0.55) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11424615 | 0.88 | ALDH1A1 (0.46) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11424611 | 0.88 | ALDH1A1 (0.46) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11413775 | 0.84 | TLR2 (0.62) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11418305 | 0.81 | TLR2 (0.50) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11418308 | 0.81 | TLR2 (0.50) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11415349 | 0.80 | ALDH1A1 (0.43) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11418731 | 0.80 | ALDH1A1 (0.47) | TLR2TLR1TLR6ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |