Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MPI | P34949 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415344 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDL3MBTL1LMNAKDM4E | |
| SCHEMBL11415330 | 0.80 | TLR2 (0.53) | ALDH1A1HPGDL3MBTL1LMNAKDM4E | |
| SCHEMBL11415326 | 0.80 | TLR2 (0.53) | ALDH1A1HPGDL3MBTL1LMNAKDM4E | |
| SCHEMBL11408875 | 0.79 | MEN1 (0.45) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL11408874 | 0.79 | MEN1 (0.45) | ALDH1A1HPGDKDM4ETSHRHSD17B10 | |
| SCHEMBL11424611 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPGDL3MBTL1LMNAKDM4E | |
| SCHEMBL11424615 | 0.78 | ALDH1A1 (0.46) | ALDH1A1HPGDL3MBTL1LMNAKDM4E | |
| SCHEMBL11408171 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HPGDL3MBTL1LMNAKDM4E | |
| SCHEMBL11408167 | 0.75 | ALDH1A1 (0.58) | ALDH1A1HPGDL3MBTL1LMNAKDM4E | |
| SCHEMBL11404916 | 0.75 | LMNA (0.50) | ALDH1A1HPGDL3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |