Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.57 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.57 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MPI | P34949 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415572 | 1.00 | TLR2 (0.57) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11410278 | 0.86 | TLR2 (0.55) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11404742 | 0.86 | TLR2 (0.55) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11413775 | 0.80 | TLR2 (0.62) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11494062 | 0.78 | CA12 (0.58) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL3364273 | 0.78 | CA12 (0.68) | ALDH1A1LMNAHPGDHTTL3MBTL1 | |
| SCHEMBL802218 | 0.78 | CA12 (0.68) | ALDH1A1LMNAHPGDHTTL3MBTL1 | |
| SCHEMBL11408171 | 0.78 | ALDH1A1 (0.58) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL11408167 | 0.78 | ALDH1A1 (0.58) | TLR2TLR1TLR6ALDH1A1LMNA | |
| SCHEMBL10090792 | 0.78 | ALDH1A1 (0.81) | TLR2TLR1TLR6ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230727-A | N-BENZYLIDENEANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4187317-A | Sunscreen and erythema treating with N-benzylidene anilenes | WILLIAM H. RORER, INC. (US) | 1980-02-05 | — | — | US | disclosed |