Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | MPI | P34949 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11408171 | 1.00 | ALDH1A1 (0.58) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL11415375 | 0.79 | PTGS2 (0.50) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL11415378 | 0.79 | PTGS2 (0.50) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL3365093 | 0.79 | MAPT (0.78) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL803097 | 0.79 | MAPT (0.78) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL11415568 | 0.78 | TLR2 (0.57) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL11416360 | 0.78 | ALDH1A1 (0.55) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL11415572 | 0.78 | TLR2 (0.57) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| SCHEMBL3369332 | 0.78 | MAPT (0.76) | ALDH1A1LMNAHPGDMAPTKDM4E | |
| Lithium SCHEMBL3369335 | 0.78 | MAPT (0.76) | ALDH1A1LMNAHPGDMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230727-A | N-BENZYLIDENEANILINE AND DERIVATIVES | WILLIAM H. RORER, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4187317-A | Sunscreen and erythema treating with N-benzylidene anilenes | WILLIAM H. RORER, INC. (US) | 1980-02-05 | — | — | US | disclosed |