Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618868 | 0.91 | NPC1 (0.37) | NPC1RAB9AALDH1A1MAPTPOLB | |
| SCHEMBL4207564 | 0.89 | NPC1 (0.36) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11616334 | 0.89 | NPC1 (0.39) | NPC1RAB9ACYP1A2TSHRALDH1A1 | |
| SCHEMBL1922438 | 0.88 | NPC1 (0.34) | NPC1RAB9ALMNAMAPK1HTT | |
| SCHEMBL11614327 | 0.88 | NPC1 (0.41) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10501883 | 0.87 | NPC1 (0.38) | NPC1RAB9ACYP1A2TSHRALDH1A1 | |
| SCHEMBL7243330 | 0.87 | FFAR1 (0.38) | NPC1RAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL3830756 | 0.87 | NPC1 (0.45) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL709631 | 0.86 | NPC1 (0.41) | NPC1RAB9ACYP1A2CYP2C9TSHR | |
| SCHEMBL29438587 | 0.86 | NPC1 (0.41) | NPC1RAB9ACYP1A2CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4220711-A | Silver halide color photographic light-sensitive element | FUJI PHOTO FILM CO., LTD. (JP) | 1980-09-02 | — | — | US | disclosed |
| US-4127586-A | HYDROXYPHENYL BENZOTRIAZOLES | CIBA-GEIGY CORPORATION (US) | 1978-11-28 | — | — | US | disclosed |
| US-4009038-A | CYAN COUPLER, A 2-(2'-HYDROXYPHENYL)BENZOTRIAZOLE | FUJI PHOTO FILM CO., LTD. (JA) | 1977-02-22 | — | — | US | disclosed |