SCHEMBL3830756

SCHEMBL3830756

CCC(C)c1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.45
RAB9A P51151 5/20 0.45
LMNA P02545 1/20 0.42
POLB P06746 2/20 0.41
CYP1A2 P05177 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
KDM4E B2RXH2 3/20 0.38
IDH1 O75874 6/20 0.37
CYP2D6 P10635 1/20 0.34
ALDH1A1 P00352 3/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
F2R P25116 1/20 0.34
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11618550 0.90 NPC1 (0.43) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL11614327 0.88 NPC1 (0.41) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL11416629 0.87 NPC1 (0.38) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL9467984 0.87 NPC1 (0.46) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL1923120 0.87 NPC1 (0.40) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL11348827 0.87 NPC1 (0.39) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL132431 0.86 CACNA1A (0.40) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL11615344 0.85 CA1 (0.36) NPC1RAB9ALMNAPOLBCYP1A2
SCHEMBL8777471 0.84 NPC1 (0.49) NPC1RAB9ALMNAPOLBTSHR
SCHEMBL11428352 0.83 NPC1 (0.51) NPC1RAB9ALMNAPOLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112608516-B Multifunctional light-stable composition and preparation method thereof 沈阳化工研究院有限公司 2022-04-08 CN claimed
CN-112608516-A Multifunctional light-stable composition and preparation method thereof 沈阳化工研究院有限公司 2021-04-06 CN claimed
CN-106471043-B UV-active chromophore functionalized polysiloxanes and copolymers made therefrom 莫门蒂夫性能材料股份有限公司 2021-01-12 CN claimed
EP-3164446-B1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2019-11-20 EP claimed
EP-3164446-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM Momentive Performance Materials Inc. (US) 2017-05-10 EP claimed
US-9562159-B2 UV-active chromophore functionalized polysiloxanes and copolymers made therefrom MOMENTIVE PERFORMANCE MATERIAL INC. (US) 2017-02-07 US claimed
WO-2016004287-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2016-01-07 WO claimed
US-20160002412-A1 UV-ACTIVE CHROMOPHORE FUNCTIONALIZED POLYSILOXANES AND COPOLYMERS MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. 2016-01-07 US claimed
US-4600632-A COPOLYMER WITH POLYSILOXANE, BLOCK POLYMERS BAYER AKTIENGESELLSCHAFT (DE) 1986-07-15 US claimed
CN-114573939-B Thermoplastic elastomer composition and preparation method and application thereof 金发科技股份有限公司 2023-09-26 CN disclosed
CN-114573939-A Thermoplastic elastomer composition and preparation method and application thereof 金发科技股份有限公司 2022-06-03 CN disclosed
CN-112608516-B Multifunctional light-stable composition and preparation method thereof 沈阳化工研究院有限公司 2022-04-08 CN disclosed
CN-112608516-A Multifunctional light-stable composition and preparation method thereof 沈阳化工研究院有限公司 2021-04-06 CN disclosed
CN-106471043-B UV-active chromophore functionalized polysiloxanes and copolymers made therefrom 莫门蒂夫性能材料股份有限公司 2021-01-12 CN disclosed
US-4283327-A USED AS A LIGHT STABILIZER CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4226763-A PHOTOSTABILIZERS HAVING GOOD HEAT RESISTANCE CIBA-GEIGY CORPORATION (US) 1980-10-07 US disclosed
US-4127586-A HYDROXYPHENYL BENZOTRIAZOLES CIBA-GEIGY CORPORATION (US) 1978-11-28 US disclosed
US-4001266-A PROCESS FOR THE MANUFACTURE OF 2-(2-HYDROXYPHENYL)BENZTRIAZOLES CIBA-GEIGY CORPORATION (US) 1977-01-04 US disclosed