SCHEMBL1922438

SCHEMBL1922438

COCC(C)c1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
LMNA P02545 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11416629 0.88 NPC1 (0.38) NPC1RAB9ALMNAMAPK1HTT
SCHEMBL1923120 0.88 NPC1 (0.40) NPC1RAB9ALMNA
SCHEMBL6834698 0.87 P2RX7 (0.31)
SCHEMBL11616334 0.86 NPC1 (0.39) NPC1RAB9ALMNA
SCHEMBL10501883 0.85 NPC1 (0.38) NPC1RAB9ALMNA
SCHEMBL7243330 0.84 FFAR1 (0.38) NPC1RAB9A
Bumetrizole SCHEMBL5439787 0.84 NPC1 (0.42) NPC1RAB9ALMNAMAPK1HTT
SCHEMBL6832895 0.83 ALDH1A1 (0.34) MAPK1
SCHEMBL19379228 0.82 PSEN1 (0.35) NPC1RAB9ALMNAMAPK1
SCHEMBL29602508 0.82 PSEN1 (0.35) NPC1RAB9ALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109838-A1 CO-STABILIZERS FOR HYDROXYPHENYL TRIAZINE STABILIZED POLYMERS BASF SE (DE) 2026-04-23 US disclosed
US-20260055243-A1 GREEN PREPARATION METHOD FOR GRANULAR PLASTIC ADDITIVES BASF SE (DE) 2026-02-26 US disclosed
WO-2024133667-A1 A METHOD FOR IMPROVING THE PROCESSING OF POLYETHYLENE BASF SE (DE) 2024-06-27 WO disclosed
WO-2024068415-A1 CO-STABILIZERS FOR HYDROXYPHENYL TRIAZINE STABILIZED POLYMERS BASF SE (DE) 2024-04-04 WO disclosed
WO-2024037903-A1 GREEN PREPARATION METHOD FOR GRANULAR PLASTIC ADDITIVES BASF SE (DE) 2024-02-22 WO disclosed
WO-2019008002-A1 PHENOLIC METAL SALTS AND THEIR PHENOLIC ACIDS AS POLYMER STABILIZERS BASF SE (DE) 2019-01-10 WO disclosed
EP-2328965-A2 FLAME RETARDANT COMPOSITIONS WITH POLYMERIC DISPERSING AGENTS BASF SE (DE) 2011-06-08 EP disclosed
WO-2010023155-A2 FLAME RETARDANT COMPOSITIONS WITH POLYMERIC DISPERSING AGENTS BASF SE (DE) 2010-03-04 WO disclosed
EP-1987094-A1 AROMATIC PHOSPHATE ACID ESTER FLAME RETARDANT COMPOSITIONS Ciba Holding Inc. (CH) 2008-11-05 EP disclosed
WO-2007096260-A1 AROMATIC PHOSPHATE ACID ESTER FLAME RETARDANT COMPOSITIONS CIBA HOLDING INC. (CH) 2007-08-30 WO disclosed
EP-1549708-A1 FLAME RETARDANT COMPOSITIONS Ciba SC Holding AG (CH) 2005-07-06 EP disclosed
WO-2004031286-A1 FLAME RETARDANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055243-A1 GREEN PREPARATION METHOD FOR GRANULAR PLASTIC ADDITIVES GRN, FUS, MAPT NPC1 2019/4885RAB9A 1066/4885LMNA 632/4885
US-20260109838-A1 CO-STABILIZERS FOR HYDROXYPHENYL TRIAZINE STABILIZED POLYMERS CBR1, H1-2, HMOX1 NPC1 2894/4885RAB9A 4850/4885LMNA 2856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.