Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.42 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422645 | 0.86 | PTGS1 (0.42) | TDP1HSD17B10LMNAL3MBTL1PTGS1 | |
| Water SCHEMBL11419837 | 0.85 | TDP1 (0.50) | TDP1HSD17B10LMNAL3MBTL1MAPT | |
| SCHEMBL11415377 | 0.85 | ALDH1A1 (0.46) | TDP1HSD17B10LMNAL3MBTL1PTGS1 | |
| Trifluoroacetic Acid SCHEMBL11417942 | 0.85 | TDP1 (0.48) | TDP1HSD17B10LMNAL3MBTL1CTDSP1 | |
| SCHEMBL8867412 | 0.83 | TDP1 (0.53) | TDP1HSD17B10LMNAL3MBTL1PTGS1 | |
| SCHEMBL8867421 | 0.83 | TDP1 (0.53) | TDP1HSD17B10LMNAL3MBTL1PTGS1 | |
| SCHEMBL9481794 | 0.83 | TDP1 (0.55) | TDP1HSD17B10LMNAL3MBTL1CTDSP1 | |
| SCHEMBL9481784 | 0.83 | TDP1 (0.55) | TDP1HSD17B10LMNAL3MBTL1CTDSP1 | |
| SCHEMBL11745051 | 0.83 | PTGS1 (0.47) | TDP1HSD17B10LMNAL3MBTL1PTGS1 | |
| SCHEMBL10890522 | 0.82 | TDP1 (0.44) | TDP1HSD17B10LMNAL3MBTL1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182868-A | 7-Methoxycephalosporin derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-01-08 | — | — | US | disclosed |
| US-4145540-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4008246-A | Aminothiazole derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-02-15 | — | — | US | disclosed |