Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8742796 | 0.86 | SMN1; SMN2 (0.60) | SMN1; SMN2PKMALDH1A1MAPTKMT2A | |
| SCHEMBL11421963 | 0.85 | KMT2A (0.66) | SMN1; SMN2PKMALDH1A1MAPTKMT2A | |
| SCHEMBL30400187 | 0.83 | RAB9A (0.61) | SMN1; SMN2PKMALDH1A1MAPTKMT2A | |
| SCHEMBL9408526 | 0.83 | RAB9A (0.61) | SMN1; SMN2PKMALDH1A1MAPTKMT2A | |
| SCHEMBL11877274 | 0.82 | POLB (0.51) | SMN1; SMN2PKMALDH1A1MAPTKMT2A | |
| SCHEMBL11331419 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11420893 | 0.81 | ALDH1A1 (0.52) | PKMALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL3459826 | 0.81 | MAPT (0.51) | SMN1; SMN2PKMALDH1A1MAPTKMT2A | |
| SCHEMBL697935 | 0.81 | ALDH1A1 (0.58) | SMN1; SMN2PKMALDH1A1MAPTKMT2A | |
| SCHEMBL29594409 | 0.81 | ALDH1A1 (0.58) | SMN1; SMN2PKMALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4189427-A | Azo dyestuffs from benzene diazo component fused to an aliphatic ring and containing two cyano substituents ortho to the azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |
| US-4048154-A | POLYAMIDE FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
| US-3978040-A | Process for the preparation of cyanoazo compounds by reacting halogenoazo compounds with CuCN in an aqueous media in the presence of a nitrogen base | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | disclosed |