Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | UNG | P13051 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418910 | 1.00 | DHODH (0.48) | DHODHCA2CA1CA12CA9 | |
| SCHEMBL11411285 | 0.88 | UNG (0.50) | DHODHCA2CA1CA12CA9 | |
| SCHEMBL11429663 | 0.83 | TSHR (0.55) | DHODHCA2CA1CA12CA9 | |
| SCHEMBL11429665 | 0.83 | TSHR (0.55) | DHODHCA2CA1CA12CA9 | |
| SCHEMBL11409879 | 0.81 | DHODH (0.48) | DHODHCA2CA1TSHRALDH1A1 | |
| SCHEMBL11409867 | 0.81 | DHODH (0.48) | DHODHCA2CA1TSHRALDH1A1 | |
| SCHEMBL11423229 | 0.79 | ALDH1A1 (0.45) | DHODHCA2CA1CA12CA9 | |
| SCHEMBL11423226 | 0.79 | ALDH1A1 (0.45) | DHODHCA2CA1CA12CA9 | |
| SCHEMBL4184857 | 0.77 | CA2 (0.56) | DHODHCA2CA1CA12CA9 | |
| SCHEMBL12694096 | 0.77 | CA2 (0.56) | DHODHCA2CA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200648-A | INFLAMMATION BY ADMINISTERING A BENZYLIDENEANILINE DERIVATIVE | WILLIAM H. RORER, INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4198349-A | ANTIINFLAMMATORY, TOPICAL | WILLIAM H. RORER, INC. (US) | 1980-04-15 | — | — | US | disclosed |