Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 8/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717778 | 0.80 | ALDH1A1 (0.51) | MAPTMEN1KMT2AKDM4ETHRB | |
| SCHEMBL10840849 | 0.79 | ALDH1A1 (0.45) | MAPTMEN1KMT2AKDM4ETHRB | |
| SCHEMBL8053689 | 0.77 | MAPT (0.41) | MAPTMEN1KMT2AKDM4ETHRB | |
| SCHEMBL10716481 | 0.76 | HTR2C (0.46) | MAPTMEN1KMT2AKDM4ETHRB | |
| Oxirane SCHEMBL11783394 | 0.75 | ALDH1A1 (0.46) | MAPTMEN1KMT2AKDM4ETHRB | |
| SCHEMBL10840472 | 0.73 | MEN1 (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10839305 | 0.72 | PGR (0.43) | MAPTMEN1KMT2AKDM4ETHRB | |
| SCHEMBL6647403 | 0.72 | AR (0.45) | MAPTMEN1KMT2AKDM4ETHRB | |
| SCHEMBL5502338 | 0.71 | AR (0.47) | MAPTALDH1A1HTTPGRAR | |
| SCHEMBL23183440 | 0.70 | ALDH1A1 (0.55) | MAPTMEN1KMT2AKDM4ETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4185151-A | 1-R-2-(U-HYDROXYALKYL-2,2,4-TRIMETHYL TETRAHYDROQUINOL-6-YL) BENZ(CD)INDOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |
| US-4000141-A | SUBSTITUTED TETRAHYDRO QUINOLINE CATIONIC DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-28 | — | — | US | disclosed |