Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57281 | 0.92 | TSHR (0.47) | TSHRPOLBAPEX1HTTTDP1 | |
| Ethylene Glycol SCHEMBL21772119 | 0.88 | TSHR (0.44) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL27371666 | 0.83 | POLB (0.42) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9334380 | 0.83 | TSHR (0.40) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10489043 | 0.81 | EPHX2 (0.37) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL15385968 | 0.79 | POLB (0.45) | KDM4EPOLBAPEX1HTTTDP1 | |
| SCHEMBL15386006 | 0.78 | EPHX2 (0.46) | THRBTSHRKDM4EPOLBAPEX1 | |
| SCHEMBL15864686 | 0.78 | TSHR (0.45) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL3784433 | 0.77 | TSHR (0.38) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL1372183 | 0.77 | HPGD (0.42) | KDM4EPOLBPABPC1APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4214047-A | Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles | EASTMAN KODAK COMPANY (US) | 1980-07-22 | — | — | US | disclosed |